When will this shit end?

[stuartbert two hats]

Oh poo. Yesterday clearly wasn't the tide decisively turning.

Edit: basically, a mixed bag where some areas are accelerating. Not what we're hoping for at this point.

Edited June 24, 2021 by stuartbert two hats

[Ozanne]

 

[Ozanne]

Small thread on hospital admissions:

 

[Toilet Duck]

10 hours ago, Supernintendo Chalmers said:

Is there data available on the level of transmission despite being double-jabbed? For example, what are the chances of someone protected against the virus and variants (to a certain degree) by being fully vaccinated but able to still transmit it? Is that even a possible scenario?

Howdy, hadn’t seen much on this, so didn’t want to speculate, but catching up on emails this evening, the study below in a letter to the NEJM was there! First reasonably large dataset I’ve seen on secondary attack rates among household contacts of vaccinated individuals…in a nutshell, after one dose of either AZ or Pfizer, about half as likely to pass it on (but also less likely to be infected). Of those that had a vaccine, 93% had only the one shot in this study, so we’ll need to wait a while to see what full vaccination looks like (cases are obviously much lower in those with full vaccination!). It’s only early data from an ongoing study, there will be much more to come from it, but it’s the best I can find at the moment to answer your question! (Kind of, I know you were asking about transmission after both jabs, but the study below probably identifies the lower bounds of the effect of vaccination on transmission).

https://www.nejm.org/doi/full/10.1056/NEJMc2107717

[stuartbert two hats]

@Toilet Duck, whilst you're here, what's the crack (or craic is you prefer) with third doses? Are they only useful as boosters for fading antibodies, or can they actually eke out a little extra immunity - making the triple jabbed even more immune than they were when double jabbed?  Obviously diminishing returns are a factor, but would it theoretically give any more advantage?  

Assuming still targeting spike on all three doses.

[Toilet Duck]

14 minutes ago, stuartbert two hats said:

@Toilet Duck, whilst you're here, what's the crack (or craic is you prefer) with third doses? Are they only useful as boosters for fading antibodies, or can they actually eke out a little extra immunity - making the triple jabbed even more immune than they were when double jabbed?  Obviously diminishing returns are a factor, but would it theoretically give any more advantage?  

Assuming still targeting spike on all three doses.

Howdy, if it’s the same sequence, then the principal benefit is keeping antibody titres up, if it’s an updated sequence with epitopes (the bits the antibodies recognise) from new variants, then it’ll expand your immunity basically! Frequent boosts would also keep parts of our cellular immunity at higher levels too (eventually we mostly just hold on to memory cells that know what to do, but take a little while to expand again and spring into action, so keeping all the other parts of the immune system on high alert is also beneficial). 

[Fuzzy Afro]

Hancock caught with his trousers down 

[Ozanne]

 

[steviewevie]

3 minutes ago, Ozanne said:

 

oh dear. I mean, don't get me wrong, I'm no fan of Hancock, but this is a bit shitty. His poor wife and kids for a start. He'll be gone now I expect.

[Kusy]

5 minutes ago, Ozanne said:

 

Real life Love Actually 

[steviewevie]

 

[Ozanne]

Just now, steviewevie said:

 

That would be a breach of the ministerial code. 

[Ozanne]

What do the NHS and Gina Coladangelo have in common?

They’ve both been fucked by Matt Hancock. 

[Ryan1984]

2 minutes ago, Ozanne said:

That would be a breach of the ministerial code. 

Does that matter with this lot? Johnson and Patel have both broken it and laughed it off.

Feels like they will keep Hancock around until ‘the end’ of the pandemic to be the sacrificial lamb/fall guy.

[tigger123]

9 minutes ago, steviewevie said:

 

Hancock really is a class A c**t isn't he

[JoeyT]

8 minutes ago, steviewevie said:

oh dear. I mean, don't get me wrong, I'm no fan of Hancock, but this is a bit shitty. His poor wife and kids for a start. He'll be gone now I expect.

The PM getting rid of Hancock for cheating on his Wife would be quite something given his own chequered past…

[Chapple12345]

 

[philipsteak]

1 hour ago, Fuzzy Afro said:

Hancock caught with his trousers down 

Surprised he could find the time, thought he was too busy saving lives

[jparx]

20 minutes ago, Ozanne said:

What do the NHS and Gina Coladangelo have in common?

They’ve both been fucked by Matt Hancock. 

😀

Dead man walking now isn’t he.

Edited June 25, 2021 by jparx

[Ozanne]

5 minutes ago, jparx said:

😀

Dead man walking now isn’t he.

He should be, but as @Ryan1984 points out that hasn’t happened to any other Ministers.  

[Zoo Music Girl]

It's very hard to see how Johnson can take the high ground on this one! Wouldn't be surprised if Hancock stays in place for a bit longer so they can oust him when more convenient. 

As an aside, why is Gillian McKeith so excited about it?!

[SheffJeff]

Do we think that Cummings leaked this story... can't believe that the Sun would have sat on it. If that's the case I wonder what he's got on BoJo that he's holding back.

[fraybentos1]

14 minutes ago, Zoo Music Girl said:

It's very hard to see how Johnson can take the high ground on this one! Wouldn't be surprised if Hancock stays in place for a bit longer so they can oust him when more convenient. 

As an aside, why is Gillian McKeith so excited about it?!

She’s a mad anti vax anti covid nutter. Not really sure why she was shared here. Check out some of her tweets if you fancy a laugh/ despairing.

[Ryan1984]

Much prefer Kathy Burke’s evaluation:

 

[Fuzzy Afro]

I don’t care that Hancock cheated on his wife. That’s a private matter for him and Mrs Hancock to address and he shouldn’t lose his job over that.

 

I care that he cheated on his wife while acting like a sanctimonious, holier than thou prick at government meetings and actively lobbying for tighter social distancing rules while not following them himself. That’s why he needs to go.