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Showing content with the highest reputation since 10/28/2020 in Posts

  1. I can’t get the following thought out of my head and it’s making the old bottom lip wobble: Wednesday evening at the 2021 festival, the sun has been out all day but temperature not stifling, perfect drinking weather. There’s already been tears at Mik Artistik, he’d mocked the crowd for being soft, thrown a few straws around and even he got choked up himself during Sweet Leaf of the North. The sun begins to set, the lights around the site start to come on and everyone is the right side of drunk. There’s a slight nip in the air but you’ve convinced yourself that you don’t nee
    25 points
  2. Howdy folks...sorry I'm late to the party! Was in a meeting and could see notifications coming up! So, looks very promising indeed. The vaccinated group not only didn't develop severe disease, but also had way fewer infections. Based on this, the suggestion is that the vaccine provides sterilising immunity (how long it lasts? far too early to say). By the numbers (94) it looks like Pfizer skipped their first planned interim analysis at 32 events and held on to get stronger data before unblinding. Appears that has paid off. They still need to wait until November 21st to get their follow up
    22 points
  3. Aw shucks!...you guys! Really I don't actually do anything. Posting here is cathartic for me too! And it's a much nicer place to be discussing these things filled with nice, reasonable people (much like the festival!) compared to some of the portals to hell that exist on the internet! Not sure if I'm supposed to say, but Neil (who is obviously really a big softie) sent me an eFests mug and T-Shirt a few weeks back to thank me for my contribution to the forum this year. A lovely and unexpected gesture that really sums this place up (Thanks again Neil!).
    19 points
  4. All European festivals worked out a solid plan for next year. And they are close to have the support of the governments in this (don't forget, governments earn a lot of money thanks to the festivals). They have the financial resources to organise a large testing scenario. If it is necessary.They can roll this out as a sort of back up. But they expect that the world will be completely different next year, thanks to the vaccines (off course, it is a big lobby campaign, they know more than we do) . If we announce this in Belgium right know, the media will find always at least 1 scientist to
    16 points
  5. No need to apologise for asking questions! So, yes they both stimulate antibodies that target the same thing, but they do it in two different ways. Basically, the coronavirus is coated with protein spikes, and this is the most recognisable part for our immune systems. We can trick our immune system into thinking it has seen the virus before if we expose it to the spike protein (then we develop immunological memory and can clobber the virus if we do get exposed to the real thing). Older vaccines did this by injecting dead virus, then we developed ways of using live virus that had been alte
    13 points
  6. Well regardless of why you voted, the result is you've made us all poorer, limited our freedoms and increased bureacracy. The idea that Brexit was set up with the noble goal of making it easier for non-EU migrants to come to the UK is beyond derision.
    13 points
  7. 11 points
  8. How come you have so many parents?
    11 points
  9. Melvin Benn is a happy man. “It feels to me like we’ve just won the lottery,” says the man behind the Reading and Leeds, Latitude and Download music festivals. The music industry veteran is reacting to today’s news that Oxford University’s Covid-19 vaccine has been proven to be up to 90 per cent effective. The boss of Festival Republic says he could barely contain his excitement when the breakthrough was announced on Radio 4 at six minutes past seven this morning. Add to this the two other potential vaccines, Prime Minister Boris Johnson’s new Covid-19 Winter Plan and Health Secretary Mat
    10 points
  10. Dan upon learning of Bidens victory:
    10 points
  11. So vaccine rollout hopefully starting 1st December. I really struggle to see a situation where we’ve had almost 2 months of people being vaccinated and then the festival announces a cancellation. I’m sure they’re over the moon with this news at Glasto HQ and feeling incredibly optimistic of a belated 50th celebration next year. And hopefully they’re on the blower to Taylor, Macca and Kenny as we speak!
    9 points
  12. 😁 though, nobody in the Pfizer trial developed severe COVID, therefore, one of their primary efficacy measures (impact on severe disease) can’t be measured yet...the Oxford trial was doing weekly swabs of participants (wasn’t in the protocol, they added it to look for sterilising immunity, but didn’t include it as an outcome just in case there was no impact)...not entirely sure whether Pfizer were doing the same, but based on what they have released today, all they can compare is infection rates between the groups as there were no other disease variables (either that or mild vs asymptomat
    9 points
  13. That's just not true though. 1. Working at home doesn't save everyone money, there are still costs associated with working at home, and not everyone has an expensive commute to work. 2. Using local authorities as an example with the exception of very few services they didn't just stop providing that service because of lockdown that's not how the provision of vital public services works. In local authorities staff get redeployed during emergencies so for example at the local authority I worked at library staff that weren't directly involved in the running of the library services whi
    8 points
  14. I work at Oxford Uni and the vice-chancellor has sent out a glowing email to all staff this morning.... Dear Colleagues and Students, Today is the day we – and people all over the globe – have been waiting for. The day when we would learn the results of the phase III trial of the Oxford Vaccine, ChadOx (ChAdOx1 nCoV-2019). The results to date suggest a composite efficacy rate of 70%: 90% for people who receive two doses of the vaccine; a half dose followed by a full dose. For people who receive two full doses of the vaccine the efficacy rate is 60%. None of
    8 points
  15. Had a read of the paper referenced above...excellent study! (I think one of the most in depth looks at the immune response to an acute viral infection ever published...ok, it’s not published yet, but it will be)...anyway, loads of interesting things in there. Essentially, the antibody response is pretty variable and not a reliable indicator of immunological memory, so seroprevalence studies may not tell us how susceptible we are to reinfection. Even though they were variable though, they were pretty durable out to 6 months (they do decline, but in many individuals, not below a level t
    8 points
  16. First the US elections, and now this. Great week This thing is obviously still far far from over, but finally some optimistic signs that 2021 will look much better than 2020
    8 points
  17. Watched the first episode of The Mandalorian last night, late to the party I know. Was a bit confused why they'd filmed it all in an alien dialect with English subtitles but enjoyed it nevertheless. Just watching the second episode and I've realised that for some reason the audio was set to Portuguese, I'm now enjoying it in English. What a tit.
    8 points
  18. 🦇👻 You are cordially invited to the creepiest efests meet yet - and that isn't just because @crazyfool1 will be wearing a dress. The Halloween special will see creatures going bump in the night (namely Dennis 🐈 of @Wellyboot fame and @squirrelarmy into a table after downing copious amounts of San Miguel), some strange sights (perhaps@Kalopsia falling asleep mid sentence) and some ancient beings may rise (don't worry @Big durbs or @Losing my hair that isn't an age reference! 🤪). 🦇👻 So join them, and possibly me, on the night of the full moon - a truly unique event (as @stuartbert two hats
    8 points
  19. I am just so angry this morning. I'm just so angry at the government for just so completely fucking this up. I've been angry at them this whole time, I was angry at them before just for being the disgusting Tories that they are, but what galls me the most is that I genuinely believe that Boris Johnson does. not. care. He does not care that this country is being ravaged by this virus. He does not care. He is bored of it. He is nowhere to be seen. He takes no responsibility. He doesn't want it to be his problem. IT FUCKING IS HIS PROBLEM. HE'S THE FUCKING PRIME MINISTER. IT IS HIS FUC
    8 points
  20. I've mentioned this many times before, but we have two people in our lives currently undergoing cancer treatment so they are not turning away patients from all areas yet. I'm pretty sure they kept up with things like chemo in the first wave. My friend, who is under 40, is undergoing it now and it's very scary for all of us. I never think they should just not treat covid patients though, that's insanely cruel and heartless. I just think we should do what we can to keep the numbers down to make hospitals safer for cancer patients and other patients with serious conditions, and also to keep up ro
    8 points
  21. Had my weekly online meeting with one of my new PhD students this morning...normally I'd get to know them a bit better as my office is right beside the lab, but this unending working from home means that now, I generally just get to talk about their project with them and don't get much chance for chit chat. Anyway, I knew he was English, but didn't really know from where (he did his undergrad at Queens in Belfast, so his address on his CV was in Belfast). He was chatting to the other Phd students and postdocs in the lab and they informed him that I went to Glastonbury every year...He gleefully
    7 points
  22. Yep totally agree with everything you’ve said, but the fact is we have to work with them to get anything done. Reality is the UK is not voting in a left wing government anytime soon. We’re in the minority. We either work with centrists and compromise on bits and pieces, or continue to treat them as the enemy, refuse to cooperate and make fuck all progress. Centrists can go either way, and they’re more likely to lean Tory if they’re the ones extending the olive branch. They’re not going to come to our side if portions of the left are slagging them off. What a portion of the far left cannot
    7 points
  23. Howdy, was in meetings all morning, so only joining the discussion now! ...why there is a different response to the different dosing regimens is unknown really. My best guess would be that it has something to do with the immune response to the chimp virus used to deliver the spike protein. This was seen with the SARS and MERS vaccines based on adenoviruses and is exactly the reason the Oxford team decided to go with a chimp virus instead of a human one (since we probably have some existing immunity to human adenoviruses). The Russian and some of the Chinese adenovirus vaccines have stuck
    7 points
  24. Making the dinner at the mo, but will have a proper look later. Can confirm though that Shane Crotty’s lab is world class (they were the ones that published the Cell paper on t-cell immunity to COVID way back). From skimming the press release, it looks like many have expected/hoped (immunity from severe disease is pretty long lasting, but memory b-cells won’t stop you catching it again once antibody levels wane...you just have the cells there to make more next time). I’d also bet a lot that cross-immunity it is what is behind mild/asymptomatic cases. Could certainly mean that a vaccine gets mo
    7 points
  25. Mass covid tests That help you enter the fest What did you expect From mass covid tests?
    7 points
  26. Even though it's looking good for Biden, I have to admit that every* point @Matt42 made was right. The shy Trump voters just ignored the polls entirely, despite all attempts to identify them, they just disengaged from the whole process. All of it about your gut, was pretty much correct, even if Trump doesn't actually win. And we (very much including myself) didn't believe you. Credit where it's due. *Apart from California, of course. That was bonkers. It was like suggesting Emile Sandé would headline the Pyramid. We all have our moments!
    7 points
  27. Well, it's not really. It has huge ramifications on our own country, trade, our political climate, as well as wider reaching issues like climate change, LGBTQI+ rights, human rights, arts and culture. These things don't exist in a vacuum.
    7 points
  28. I won't be staying up as I have my 2nd heart operation early Thursday morning, so I need my sleep. Not sure which I fear most: dying on the operating table or 4 more years of Trump! 😄
    7 points
  29. And breathe. I'm not downplaying seriousness at all. At all. What I'm referencing is the difference between emergency care, where something requires immediate treatment as a result of something happening then and there, and a longer term care plan such as cancer. That's in no way a commentary or opinion on which is more or less serious, and as you may have guessed I find it incredibly offensive and upsetting to suggest that I view cancer as not serious. Please don't do that again. The NHS care model for the two things, as I understand it, is to treat as a priority those things
    7 points
  30. Yeah - nice buzz, mild visuals nothing heavy, lasts about eight hours. Would recommend. Oh the vaccine? Sorry no
    6 points
  31. In vaccine news, somebody asked previously how long between EUA submission and authorisation being granted...had a chat with a friend in the Biotherapeutics unit at Pfizer Dublin, they are doing the QA on the vaccine being made in Belgium to get it ready to ship widely. Expecting this to be middle of December she said. FDA and EMA jointly looking at the emergency use submission, so should be a coordinated approval in both jurisdictions (if it's before January 1st, this is sufficient for EUA in the UK, afterwards, the MHRA will have to either accept the EMA authorisation or conduct their own as
    6 points
  32. Trust me I get what you are saying however the last public sector pay freeze went on for 8 years and only ended in 2018. So for those people it might be hard to rationalise it that at least they have a job (I’m surmising). Another factor I think that makes this even more of a joke is that the Government can waste millions on contracts that give large payout to consultants or their friends yet can’t find the money to give public sector workers pay rises. They have found another £21.5b for defence funding and this is also whilst MPs will be getting a pay rise as well. It’s disgraceful
    6 points
  33. Honestly hoping corbyn does apologise and I hope he does it like this: IMG_1877.mp4
    6 points
  34. I’ve got a close friend whose working 14 hour days in ICU on the front line. She also has diabetes and an has insulin pump to keep her sugar levels regulated. She should really be in the shielding category but instead she’s right in the thick of it caring for those who have been hit the hardest. Just to add to it, she’s South American so one of those “immigrunts” that brexiteers don’t think should be in this country. Nurses should be getting free drinks for life for the work they’re doing right now.
    6 points
  35. Forgive me, but I am going to visit my Mum tomorrow before she gets put into full lockdown. She's just south of Glasgow and I'm in Edinburgh. I think she needs me and i need to see her. She had a fall recently and is still in pain and her little dog is poorly. I can't bear not seeing her. it's my birthday next Monday and it's a milestone one, so we are both struggling emotionally 😢
    6 points
  36. Thanks We are in a form of lockdown over in NI but there were a few things we could still do together over here and a few places we could go to visit. I told her on Tuesday night to pack a bag and we would have a one night getaway the next day. She didn't know where we were going. I had booked us a night in these cool bubble dome things on Lough Erne, essentially you sleep in a huge bubble dome in the forest and can see the stars above you, etc. Once we arrived, we went on a walk around the grounds and I 'popped the question' on a little boardwalk out on to the lough. Thankfull
    6 points
  37. I just find it weird, that out of all the people in the world, all the crimes and awful things done, some people still feel the need to endlessly lay into Jeremy Corbyn, and think after all the perpetual vilification of the last few years, he's even now supposed to collapse on his knees and plead for forgiveness and acknowledge he is the greatest monster of modern times rather than defend himself in any way.
    6 points
  38. The hard left in the whole are willing, and quite rightly so, to believe the anecdotal and personal evidence presented in the discourse of the #MeToo movement, in order to bring the downfall of the misogynistic and toxic hegemonic nature of institutions like Hollywood. Yet when the same thing has occurred in the Labour Party, where victims of blatant anti-semitism have made complaints that are brushed under the carpet, they yell 'where's the actual evidence. I need the social media posts, the WhatsApp messages, not the evidence of plenty of Jewish Party members and MPs'. It's a horrible
    6 points
  39. So its Halloween 🎃 zoom this weekend!! You can wear a mask 😷 Or sit in the dark 👻 Or cover your face 🙈 Or use a filter 🤩 Or be a crow! 🐦 (hi Arthur!) Or a princess 👸 Or a cowboy 🤠 Or a cat 🐈 Or wear something fun 🥳 Or wear your jarmas 😴 Or join without your camera on if you want! 📷 Or if you're scary looking anyway (like squirrel 🐿) you don't need to do anything!! You can come as yourself! You can come in disguise! (You don't need to do any of the above if u don't wanna) But you should come and say hello! EVERY
    6 points
  40. Biden's top 3 priorities for his first year in office are a more collegiate approach to foreign policy, restoration of WHO membership and safeguarding indie music festivals.
    5 points
  41. It will impact globally (and effect us here in the UK), but also it's not like I stop caring about people because they live in another country- a lot of people will die from Trumps covid policy, a lot of people will suffer due to the bigotry he emboldens- why would I not be emotionally invested in the outcome?
    5 points
  42. After a fairly shit year I got engaged on Wednesday so I now have something good to look back on in 2020
    5 points


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